Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood
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چکیده
منابع مشابه
Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood.
Refractory cytopenia of childhood is the most common type of childhood myelodysplastic syndrome. Because the majority of children with refractory cytopenia have a normal karyotype and a hypocellular bone marrow, differentiating refractory cytopenia from the immune-mediated bone marrow failure syndrome (very) severe aplastic anemia can be challenging. Flow cytometric immunophenotyping of bone ma...
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Introduction Bone marrow examination is essential procedure for evaluation of a variety of clinical hematologic disorders and for preclinical toxicity studies of anticancer compounds and immunosuppressive agents [1,2]. This evaluation has been classically performed by morphologic assessment of bone marrow aspiration smears and core biopsy specimens by use of light microscopy. Differential cell ...
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Myeloid sarcoma of female breast is a rare presentation of acute myeloid leukemia (AML). The tumor mass may precede or occur concurrently with AML, CML, myeloproliferative disorders, and/or myelodysplastic syndromes. Histologically, it looks like a large cell lymphoma and can be misdiagnosed. A case refe...
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Standardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful cross-study and cross-center comparison of data. Experts developed five standardized, eight-color panels for identification of major immune cell subsets in peripheral blood. These were produced as pre-configured, lyophilized, reagents...
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OBJECTIVE To provide an overview of the utility of flow cytometry for phenotyping of acute leukaemias and selection-of monoclonal antibodies. DATA SOURCES The literature review was obtained through internet, journals and chapters in the relevant books. DATA SELECTION Relevant articles and chapters on immunophenotyping of acute leukaemias were selected from respected international journals a...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2014
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2014.107706